Human Sera
Cayman Chemical Terbutaln 50mg
A β2-adrenergic receptor agonist; an active metabolite of bambuterol; binds to β1-, β2-, and β3-ARs (Ki = 31.3, 15.4, and 79.8 nM, respectively); selectively increases adenylyl cyclase activity in CHO cell membranes expressing recombinant human β2- or β3- over β1-ARs at concentrations 100-fold greater than the respective Ki values; inhibits airway obstruction induced by methacholine or LTD4 in anesthetized guinea pigs
Cayman Chemical StramustIn PhosphatSodIu 100mg
A derivative of estradiol that destabilizes microtubules (Kds = 10 and 15 µM for MAP-1 and MAP-2, respectively); induces cell cycle arrest in mitosis at the metaphase stage in DU145 and PC3 prostate cancer cells; induces apoptosis in U87MG human malignant glioma cells
Cayman Chemical CefonIcIdodIum salt 100mg
A broad-spectrum antibiotic with a prolonged serum elimination half-life in animals
Cayman Chemical UDPD-GlucosesodIum salt 100mg
A nucleotide sugar and P2Y14 receptor agonist; induces inositol phosphate production in COS-7 cells expressing the human P2Y14 receptor (EC50 = 0.588 µM)
Cayman Chemical BromadIolon 100mg
A second generation anticoagulant rodenticide; an inhibitor of VKOR that inhibits blood clotting; inhibits human VKORC1 (IC50 = 1.6 nM); toxic to rodents, including mice (LD50 = 1.75 mg/kg) and rats (LD50s = 1.05 and 1.83 mg/kg for males and females, respectively); does not significantly affect breeding performance in mice at 70% of the LD50 value
Cayman Chemical 1PalmItoyl2Oleoylsnglyce 50mg
A phospholipid; a major component of E. coli bilayers; vesicles composed of 1,2,-POPE can be disrupted by polycationic antimicrobials; has been used in combination with other lipids in the formation of LNPs for spleen- and liver-specific targeting in mice
Cayman Chemical Cambendazol 50mg
An antihelmintic agent; eradicates S. ratti adult worms from intestine and S. stercoralis larva from muscle at a dose of 50 mg/kg/day; inhibits polymerization of microtubules isolated from bovine brain (IC50 = 64.2 µM)
Cayman Chemical OxyphenonIumbromIde 100mg
A muscarinic acetylcholine receptor antagonist (Kds = 0.11 and 0.17 nM for guinea pig atria and ileum, respectively); reverses carbaminocholine- and acetylcholine-induced decreases in blood pressure in anesthetized cats (ED50s = 0.591 and 1 μg/kg, respectively); decreases rumenal ulcer formation in rats and suppresses insulin-induced gastric secretion in dogs with gastric fistulas; prevents FDM in a chick model of experimental myopia
Cayman Chemical CyntrnIlIprole 50mg
An anthranilic diamide insecticide; an allosteric RyR activator; 300- to 500-fold selective for insect over mouse RyR1, greater than 2,000-fold selective for insect over rat RyR2, and inactive in human IMR32 cells expressing RyR2 and RyR3; active against the diamondback moth (PP50 = 0.1 ppm); induces mortality of the green peach aphid, cotton melon aphid, and white fly (EC50s = 1.1, 0.4, and 5.8 ppm, respectively)
Cayman Chemical Capsacn 100mg
A terpene alkaloid; induces inward currents in HEK293 cells expressing rat TRPV1 (EC50 = 0.64 µM at neutral pH); decreases LPS-induced PGE2 production, as well as reduces LPS- and IFN-induced NO release in isolated mouse peritoneal macrophages at 10 and 50 µM; induces substance P release in rat spinal cord slices (EC50 = 2.3 µM); reduces acetylcholine- or phenylquinone-induced writhing (ED50s = 1.33 and 1.38 mg/kg, respectively, s.c.) but has no effect on the latency to paw withdrawal in the hot plate test in mice (ED50 = >20 mg/kg, s.c.)
AdipoGen BioStab Antibody Stabilizer
Free or conjugated antibodies are often used in immunoassays, either in the system specific detector antibody plus streptavidin-HRP or in the system analyte-specific antibody plus species-specific antibody-HRP-conjugate. Both systems allow a high flexibility at lower costs. BioStab Antibody Stabilizer dramatically extends the life of your valuable antibodies, allowing much more consistent results over extended periods of time compared to daily prepared dilutions. BioStab Antibody Stabilizer can be used in ELISA, Western Blotting, Immunohistochemistry and any other applications which require marker or biotinylated antibodies. It is supplied as a ready-to-use solution for dilution of antibodies. This stabilizer contains a minimum amount of a surfactant. The stabilizer is free of any protein to minimize potential unspecific interactions. The method below is strongly recommended for standard assay procedures and reduces loss of valuable conjugates and assay-to-assay variations.
Cayman Chemical BetaIn AldehydechlorIde 50mg
The physiological intermediate in the oxidation of choline to betaine
Cayman Chemical CarboxyPTIOpotasIum salt 100mg
Carboxy-PTIO is a NO scavenger. It reacts stoichiometrically with NO and can be used for EPR detection of NO.{1203,4117}
Cayman Chemical Incensole Acetate 50mg
A diterpene with diverse biological activities; a TRPV3 activator (EC50 = 16 µM for inducing calcium influx in HEK293 cells expressing TRPV3); inhibits IκBα degradation in TNF-α-stimulated HeLa cells at 60-140 µM; reduces amyloid-β (25-35) peptide-induced apoptosis, increases in MDA levels, and the production of ROS; reduces paw edema in a mouse model of hind paw inflammation at 50 mg/kg; has anxiolytic and antidepressant-like activity in mice